Resources for Assay Development and High Throughput Screening

Descriptions of assay formats that are compatible with HTS
Selection and development of optimal assay reagents
Optimizations and troubleshooting for assay protocols with respect to sensitivity, dynamic range, signal intensity and stability
Adaptations of assays for automation and scaling to microtiter plate formats
Instrumentation
Sources of assay artifacts and interferences
Statistical validation of assay performance parameters
Secondary assays for chemical probe validation and SAR refinement
Data standards for reporting the results of screening and SAR assays
In vivo assay development and validation