**Next Round of MDG -

Summer 2021**

Check back for RFA

 

• "Marley's marvelous success"

https://msutoday.msu.edu/news/2021/marleys-marvelous-success

• "The novel rexinoid MSU-42011 is effective for the treatment of preclinical Kras-driven lung cancer" Moerland et al., Scientific Reports, December 2020

https://www.nature.com/articles/s41598-020-79260-8

• "Hyperphosphorylated tau aggregation and cytotoxicity modulators screen identified prescription drugs linked to Alzheimer's disease and cognitive functions" Liu et al., Scientific Reports, October 2020

https://www.nature.com/articles/s41598-020-73680-2

• MSU COLLABORATES TO UNDERSTAND AND TARGET COVID-19 CORONAVIRUS HOST CELL ENTRY

• "Inhibiting Mycobacterium tuberculosis DosRST signaling by targeting response regulator DNA binding and sensor kinase heme" Zheng et al., ACS Chem. Biol. March 2020

https://doi.org/10.1021/acschembio.8b00849

 

• High throughput screening
• Automated laboratory robotics
• Hit selection

• Efficacy testing in normal & disease models
• Safety testing
• Imaging
• In vivo techical assistance
• PK studies 

• Active pharmaceutical ingredient development
• Screening & target validation
• Series identification & Scale-up