• MSU DD Seminar Series: Dr. John Beutler (NIH/NCI), Friday, October 23, at 9am 

• "Hyperphosphorylated tau aggregation and cytotoxicity modulators screen identified prescription drugs linked to Alzheimer's disease and cognitive functions" Liu et al., Scientific Reports, October 2020

https://www.nature.com/articles/s41598-020-73680-2

• MSU COLLABORATES TO UNDERSTAND AND TARGET COVID-19 CORONAVIRUS HOST CELL ENTRY

• "Inhibiting Mycobacterium tuberculosis DosRST signaling by targeting response regulator DNA binding and sensor kinase heme" Zheng et al., ACS Chem. Biol. March 2020

https://doi.org/10.1021/acschembio.8b00849

• "Identification of New MmpL3 Inhibitors by Untargeted and Targeted Mutant Screens Defines MmpL3 Domains with Differential Resistance" Williams, et al., Antimicrobial Agents and Chemotherapy Sept. 2019

https://aac.asm.org/content/63/10/e00547-19.long

 

 

• High throughput screening
• Automated laboratory robotics
• Hit selection

• Efficacy testing in normal & disease models
• Safety testing
• Imaging
• In vivo techical assistance
• PK studies 

• Active pharmaceutical ingredient development
• Screening & target validation
• Series identification & Scale-up