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Assay and Model Overview

Assay and Model Overview

The MSU In Vivo Facility offers an extensive list of models and capabilities to suit your efficacy, and early safety testing needs. As part of a large university with a highly respected pharmacology department, a high ranking veterinary teaching and research hospital, and other state-of-the-art facilities, we are able to offer a wide range of in vivo models in rodent and non-rodent species. Please contact us for more information or to discuss our additional capabilities.

  • Acute and Subchronic Toxicity
     
  • Early Target Organ Identification
     
  • In Vivo Pharmacokinetic Studies
     
  • Cardiovascular
    • Radiotelemetry
    • Myocardial Infarction
    • Heart Failure
    • Ischemia/Reperfusion
    • Electrophysiology
    • Pulmonary Artery Hypertension
       
  • Neurologic
    • Locomotor Activity
    • Microdialysis
    • Stereotaxic Neurosurgery/Lesioning
    • Cognition
    • Stroke
       
  • Ocular
    • Neovascularization
    • Ocular Endpoints for Toxicology Studies
       
  • Pulmonary
    • Asthma/Methacholine
    • Pulmonary Fibrosis
    • Cystic Fibrosis
    • Pulmonary Hypertension
       
  • Gastrointestinal
    • Colonic Balloon Distension
    • Transit Time/Gastric Emptying
    • Nerve/Muscle Preparations
    • Spatiotemporal Analysis of Peristalsis/Movement
       
  • Renal
    • Blood Flow
    • Ischemia/ Reperfusion
    • Renal Function
       
  • Vascular
    • Systemic Hypertension
    • Peripheral Artery Disease
       
  • Oncology
    • Solid Xenografts
    • Hematogenous Xenografts
       
  • Immunology
    • Immunophenotyping
    • Cytokine/Chemokine Analysis
    • Ex Vivo Immune Function
    • Respiratory Burst/Phagocytosis
    • Immunoglobulin Isotyping
    • Antigen-Specific Antibody Response
    • Cell-Based Assays
    • Pharmacodynamic Assay Development
       
  • Imaging
    • Radiography
    • Fluoroscopy
    • Echocardiography
    • CT and Micro CT
    • MRI
    • MRS
    • PET
    • Nuclear Scintigraphy
    • IVIS in vivo bioluminescent and fluorescent imaging
    • VEVO rodent high frequency ultrasound
       
  • Rodent Stem Cell Models