The MSU In Vivo Facility works with academic clients to test novel compounds, therapeutics,
and devices. We offer a talented and experienced team to assist with the in vivo components
of your research, thereby streamlining your project. Our services include testing
using established in vivo models, development and refinement of in vivo assays, authoring
and managing IACUC approved research protocols, and providing Letters of Support for
The guiding principles for in vivo research are the three Rs, and the MSU In Vivo
Facility assists researchers in following this doctrine. Our experts can help you
select the most efficient models for your project and identify alternative methods
where appropriate. In addition, our experienced scientists are proficient in a variety
of techniques, meaning more information from smaller data sets, and a reduced need
for training. Ultimately, working with the MSU In Vivo Facility helps to save lives
as well as costs.
The MSU In Vivo Facility provides support for the majority of the preclinical stages
of drug discovery, from initial target identification and validation through assay
development and lead optimization to the selection of a candidate molecule for clinical
development. Our skilled scientists are trained in a variety of models to generate
and report your data, and our experts can apply years of industry experience to help
you select the models best suited to your project.
Novel drugs and devices may need novel methods to test safety, efficacy, or other
characteristics, or to satisfy budget or timeline constraints. The experts at the
MSU In Vivo Facility routinely develop custom models and evaluations to fit a wide
range of research needs.
The MSU In Vivo Facility has a great deal of experience in drafting, amending, and
updating AUPs, and in managing the IACUC approval process. Many models are already
covered under our existing AUPs or simply require an amendment. Working with the MSU
In Vivo Facility saves time and resources in the preparation, review, and approval
of these documents.
The MSU In Vivo Facility routinely drafts letters of support for grant proposals from a variety of grant institutions, including the NIH. Our experts may have previous experience in the model or assay being utilized, which lends credibility to your proposal and helps to assure reviewers that you have the necessary resources to meet objectives.